A Beginner's Guide to Blood Cells, Second Edition by Barbara J. Bain

By Barbara J. Bain

This renowned notebook has been up-to-date and increased all through, delivering a concise view of diagnostic haematology, in a handy and sensible format.A Beginner's advisor to Blood Cells is a perfect for;Trainee laboratory technicians and scientists scholars learning the body structure or pathology of the blood these getting ready for haematology examinationsWhy purchase This Book?Unique pocket advisor, written via Barbara Bain – a world-renowned professional within the box of blood morphology Outlines the fundamentals of diagnostic haematology contains a useful self-assessment part re-creation – now comprises additional information on medical elements and additional checks

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Monocytes can show increased size and cytoplasmic vacuolation during infection. Immature monocytes with increased gran- Fig. 11 Eosinophil leucocytosis with one of the three eosinophils being markedly hypogranular. 54 Chapter 3 ulation and cytoplasmic basophilia can occur both in infections and in leukaemia and related conditions. Eosinophils can show a variety of morphological abnormalities (Fig. 11) including hyper- and hypolobulation, reduced granulation and cytoplasmic vacuolation. g. in parasitic infection) and also in eosinophilic leukaemia so they are not useful in differential diagnosis.

They have a lower nucleocytoplasmic ratio and the cytoplasm is pink and slightly granular rather than reddish-brown. It is impossible to give any reliable opinion of films showing storage artefact. If the blood count is normal they can usually be ignored but if there is any reason to suspect a haematological abnormality a fresh blood sample must be obtained. A common cause of inaccurate blood counts is partial clotting of the specimen or aggregation of the platelets. e. the process of blood clotting has started) or because there is an antibody present in the plasma which leads to platelet aggregation in blood that is anticoagulated with ethylenediaminetetra-acetic acid (EDTA).

3 Thrombocytosis (in chronic granulocytic leukaemia). The platelets also show increased variation in size and some are agranular. 48 Chapter 3 Neutrophils may have congenital or acquired abnormalities of nuclear lobulation. An increase in band forms and less lobulated neutrophils in relation to more mature, well-lobulated neutrophils is known as a left shift (Fig. 4). This term is also used when neutrophil precursors are present in the blood. Neutrophils Fig. 4 Toxic granulation, vacuolation and left shift (the two white cells are band forms).

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